Beilstein J. Nanotechnol.2023,14, 339–350, doi:10.3762/bjnano.14.29
properties, drug loading, and drug release are discussed. We highlight the utilization of ethylcellulose, poly(lactic-co-glycolic acid), and polyurethane/polyurea in the field of nanomedicine as potential drug delivery systems. Advances are still needed to achieve better control over size distribution
, nanoparticle concentration, surface functionalization, and the type of polymers that can be processed.
Keywords: ethylcellulose; nanoemulsions; nanomedicine; phase inversion composition (PIC) method; PLGA; polymer nanoparticles; polyuria; polyurethane; surfactants; Review
1 Introduction
The field of
interest mainly prepared by nanoemulsification/evaporation.
3 Preparation of polymer nanoparticles by low-energy emulsification
3.1 Ethylcellulose nanoparticles
Ethylcellulose is a biocompatible and FDA-approved polymer (a chemical substance generally recognized as safe) widely applied within the
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Figure 1:
Schematics of the structural and curvature changes during (a) PIT and (b) PIC nanoemulsification.